Effects of αβ-amirona on inflammation in topical edema ear model in mice

Introduction In vivo models of inflammation are definitely the best tools to study the biological role, because no other approach will allow the simultaneous investigation of cells and mediators that interact during the inflammatory process. Several reports in the literature have shown the efficacy of a, b-amyrin, the main component of the resin plant of the genus Protium in studies with in vitro models of inflammation. Another component of this resin with anti-inflammatory activity is the ab-amirona, but this is still less studied. Objective: To evaluate the topical anti-inflammatory activity of the compound isolated ab-amirona in models of skin inflammation in mice.